Lectures on Developmental Physiology by Alfred Kühn

By Alfred Kühn

"1 Jind released lectures insipid. " ALEXANDER VON HUMBOLDT ta LOUIS AGASSIZ, January 15, 1840 many stuff converse opposed to the ebook of lectures. The impression of the spoken note is especially diversified from that of the written note. Repeated recapitulations, which aid the listener lower than­ stand, are pointless, and the overtones of speech disappear in print. A lecture, quite while now not intended for newcomers and never provided in instruction for a try, allows the privilege of subjective selection, and whilst released it truly is rightly open to feedback. So it has no longer been effortless for me to figure out to submit those lectures, which i've got given in quite a few types in Gattingen after which back in Tiibingen. in any case, the finding out components have been the urging of my scholars, the encouragement of associates, a lot of whom i used to be thrilled to determine between my listeners, and the want of my writer, with whom i've got loved a pleasant courting for a very long time. the ultimate type of the textual content is essentially a duplicate, and hence reallectures are the guts of it. If the lectures had now not been taken down time and again, this e-book don't have seemed; 1 couldn't have undertaken a textbook-sized compilation of this fabric. With all of the adjustments, the association, the road of notion, and of ten the composition of the lectures themselves have been retained. they might bear in mind to my listeners of previous the hours we spent jointly.

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6··O~ . i . . \ \. \ g . . ~~( /. ' ' ..... \ .... ,.. :: . , '. '. ~ ~~'~'~ "". i';' ·:··:'::,Q "w\ '", . ';'... '. '.... ( . :. :.. __ ~/ c b Fig. 54. First cleavage metaphase of Cyclops americanus. a normal; b centrifuged; c centrifuged first spermatocyte division of Homarus. (After SCHRADER, 1934) entirely (Fig. 55d-f). The preparations of the fixed, centrifuged spindle figures show that the fibers have a certain tensile strength and that the chromosomes are attached to particular fibers.

Direction of force is downward in ali figures. a resting nuc\eus; b-f metaphase and early anaphase 2,000 x . (After BEAMS and KING, 1936) When metaphase spermatocytes are placed in a slightly hypertonic solution, the ceH shrinks, and the cytoplasm, which has now lost water of imbibition, lies in a thin coat around the nuclear division figure (Fig. 57 c, d). The ability to divide is not disturbed by moderate shrinking. The changes are reversed when the cells are restored to an isotonic medium. At higher osmotic strengths, the water of hydration is removed from the spindle as well.

After BIER, 1957) c b d t Fig. 25. Salivary ehromosomes of Drosophila melanogaster. a somatie pairing of a normal X-ehromosome and one with a deletion; b deletion in some of the ehromonemata resulting from X-irradiation during ehromonemal replication (5-12 hours after egg deposition); e-d diagram of the origin of the deletion in the 8 ehromonema stage. (a after PAINTER, 1933; b-d after SLlZYNSKI, 1947) longitudinal contraction, so that they now correspond to metaphase chromosomes (Fig. 24). These are already very numerous in the relatively small nuclei; the salivary gland chromosomes must eontain many more ehromonemata, eertainly hundreds (ef.

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Lectures on Developmental Physiology by Alfred Kühn
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