By Raymond C. Valentine, David L. Valentine
The physical-chemical houses of the omega-3 fatty acid DHA (docosahexaenoic acid) let it to facilitate fast biochemical techniques within the membrane. This impact has a number of merits, together with these enthusiastic about the expansion of micro organism, quick power new release, human imaginative and prescient, mind impulse, and photosynthesis, to call a number of. but DHA additionally contains hazards that may bring about mobile demise and disorder. Omega-3 Fatty Acids and the DHA precept explores the jobs of omega-3 fatty acids in mobile membranes starting from human neurons and swimming sperm to deep sea micro organism, and develops a precept wherein to evaluate their merits and hazards. ? The DHA precept states that the mixing of lipids to shape mobile membranes is evolutionarily-honed to maximise gain whereas minimizing possibility, and advanced mixing code regarding conformational dynamics, power tension, strength yield, and chemical balance underlies all mobile membranes. ? This ebook lays the foundation to figuring out this code. It examines the evolution of DHA and the membrane and explores the overall houses of omega-3s and different membrane lipids. It then makes a speciality of mobile biology earlier than transferring to a pragmatic dialogue on functions. The authors talk about the DHA precept as utilized to petroleum degradation, winemaking, worldwide warming, molecular farming, getting older, neurodegenerative illnesses, and the prevention of colon melanoma. Reflecting the elevated public curiosity that has emerged through the years, this quantity makes use of an integrative method of clarify the advanced roles of omega-3s within the membrane. Incorporating ideas from chemistry, mobile biology, evolution, and ecology, this paintings supplies researchers in quite a few fields the development blocks to stimulate extra learn. ?
Read or Download Omega-3 Fatty Acids and the DHA Principle PDF
Similar physiology books
Medical Physiology: Principles for Clinical Medicine
Scientific body structure provides the physiological suggestions necessary to medical drugs. each one bankruptcy presents conceptual diagrams to facilitate comprehension of adverse options, and offers either general and irregular medical stipulations to demonstrate how body structure serves as a huge foundation for prognosis and remedy.
Seeds: Physiology of Development and Germination
Because the book of our monograph on seed body structure and biochemistry (The body structure and Biochemistry of Seeds on the subject of Germination, Sprin ger-Verlag, 1978, 1982), it's been instructed to us textual content overlaying a similar topic region will be applicable. This booklet is our reaction. not like the former volumes, even though, this article isn't meant to be both a serious or a accomplished account.
Carotenoids: Volume 4: Natural Functions
The Carotenoids publication sequence presents targeted debts of the basic chemistry of carotenoids and the fundamental equipment utilized in carotenoid study, and demanding discussions of the biochemistry, capabilities and purposes of those vital compounds. quantity four and its spouse, quantity five, care for the capabilities of carotenoids in every kind of residing organisms and the activities of carotenoids in human food and overall healthiness.
Multiscale Simulations and Mechanics of Biological Materials
Multiscale Simulations and Mechanics of organic fabrics A compilation of modern advancements in multiscale simulation and computational biomaterials written by way of major experts within the fieldPresenting the most recent advancements in multiscale mechanics and multiscale simulations, and delivering a distinct point of view on multiscale modelling of organic fabrics, this ebook outlines the newest advancements in computational organic fabrics from atomistic and molecular scale simulation on DNA, proteins, and nano-particles, to meoscale gentle subject modelling of cells, and to macroscale gentle tissue and blood vessel, and bone simulations.
Additional info for Omega-3 Fatty Acids and the DHA Principle
Example text
Sklar, D. L. White, and E. A. Dratz. 1979. Disaturated and dipolyunsaturated phospholipids in the bovine retinal rod outer segment disk membrane. Biochim. Biophys. Acta 552:294–306. , and R. A. Cone. 1974. Lateral diffusion of rhodopsin in the photoreceptor membrane. Nature 247:438–441. Valentine, D. L. 2007. Adaptations to energy stress dictate the ecology and evolution of the Archaea. Nature Rev. Microbiol. 5:316–323. Valentine, R. , and D. L. Valentine. 2004. Omega-3 fatty acids in cellular membranes: A unified concept.
L. C. , A. J. M Driessen, and W. N. Konings. 1998. The essence of being extremophilic: The role of the unique archaeal membrane lipids. Extremophiles 2:163–170. van de Vossenberg, J. L. C. , T. Ubbink-Kok, M. G. L. Elferink, A. J. M. Driessen, and W. N. Konings. 1995. Ion permeability of the cytoplasmic membrane limits the maximum growth temperature of bacteria and archaea. Mol. Microbiol. 18:925–932. © 2010 by Taylor and Francis Group, LLC of DHA 3 Coevolution Membranes and Their Proteins Hypothesis: Sensory perception in humans would not be possible without DHA and other polyunsaturated chains that drive rapid collisions among or between membrane proteins and enzymes.
Prog. Lipid Res. 27:153–175. , A. Relini, and P. -G. Chong. 2002. Structures and permeability properties of biomimetic membranes of bolaform archaeal tetraether lipids. J. Memb. Sci. 206:131–147. , and D. Lovely. 2003. Extending the upper temperature limit of life. Science 301:934. Miljanich, G. , L. A. Sklar, D. L. White, and E. A. Dratz. 1979. Disaturated and dipolyunsaturated phospholipids in the bovine retinal rod outer segment disk membrane. Biochim. Biophys. Acta 552:294–306. , and R. A. Cone.
