By Neil S. (Ed.) Skolnik, Neil S. Skolnik
This new quantity within the present scientific perform™ sequence places crucial evidence-based, nationally famous medical guidance jointly in a single position. hence, busy clinicians can visit one resource whilst, within the care of a sufferer, a query arises that's top replied by means of an present medical instruction. one of the subject matters coated during this quantity are hyperlipidemia, administration of newly clinically determined atrial traumatic inflammation, antithrombotic remedy for venous thromboembolic ailment and atrial traumatic inflammation, and prevention of bacterial endocarditis. The e-book information remedy for bronchial asthma and infectious ailments starting from pneumonia to tuberculosis to diarrhea. the quantity additionally includes chapters on endocrinology, gynecology, neurology, and psychiatry. With the busy clinician in brain, crucial perform directions in basic Care has been constituted of its starting place to have a better half PDA source, with summaries of the information during this e-book and extra summaries of guidance no longer incorporated within the publication. (The PDA model of crucial perform instructions in fundamental Care is out there from the writer, ISBN 1-934115-47-9.) jointly, those complimentary textbooks, in print and digital structure, should still facilitate the implementation of nationally well-known scientific instructions.
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Additional info for Essential Practice Guidelines in Primary Care (Current Clinical Practice)
Sample text
Pepine CJ. (2004) What is the optimal blood pressure and drug therapy for patients with coronary artery disease? JAMA 292:2271–2273. Granger CB, McMurray JJ, Yusuf S, et al. (2003) Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensinconverting-enzyme inhibitors: the CHARM-Alternative trial. Lancet 362:772–776. UK Prospective Diabetes Study Group (1998) Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38.
Table 3 Doses of Statin Required to Obtain a 30–40% LDL-Cholesterol Reduction Drug Atorvastatin Lovastatin Pravastatin Simvastatin Fluvastatin Rosuvastatin Dose (mg/d) LDL reduction (%) 10 40 40 20–40 40–80 5–10 39 31 34 35–41 25–35 39–45 Alternative classes of antihyperlipidemia therapy include nicotinic acid, bile–acid sequestrants, and ezetimibe. These agents should be considered as second-line therapies or, perhaps, first-line therapy for those with intolerance to statins. In addition, some of these agents may be more beneficial should dyslipidemia (depressed HDL, elevated TG) rather than hyperlipidemia exist.
1. Table 11 Treatment of Chronic Hypertension in Pregnancy Antihypertensive class Methyldopa β-blockers Labetalol Clonidine CCB Diuretics ACE inhibitors ARBs Comment Preferred based on long-term follow-up studies supporting safety Reports of intrauterine growth retardation (atenolol) Generally safe Increasingly preferred to methyldopa because of reduced side effects Limited data Limited data No increase in major teratogenicity with exposure Not first-line agents Probably safe Contraindicated Reported fetal toxicity and death ACE, angiotensin-converting enzyme; ARBs, angiotensin receptor blockers.
