By Gaetano Santulli
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Additional resources for Angiogenesis: Insights from a Systematic Overview
Example text
The blood and lymphatic systems complement each other to maintain tissue homeostasis; an interdependence that is also reflected in their coordinated development during embryogenesis. [12, 69] As first described by Florence Sabin in 1901, the lymphatic vessels arise in mid-gestation after the development of the blood vascular network from progenitor cells in the cardinal vein. Subsequent to the formation of the lymph sacs, progressive expansion of lymphatic vessels occurs by active sprouting, in a manner similar to blood vessel sprouting, but under regulatory control of a different cast of molecules.
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